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Genome editing can introduce designed mutations into a target genomic site, but also into unintended off-target sites. DAJIN, a novel nanopore sequencing data analysis tool, identifies and quantifies allele numbers and their mutation patterns, reporting consensus sequences and visualizing mutations in alleles at single-nucleotide resolution.
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2. Consequences of Stroke in Elderly Stroke Survivors. The incidence of stroke disease increases with age, in both men and women with approximately 50% of all strokes occurring in people over age 75 and 30% over age 85 [1, 3, 4].Stroke is among the top leading causes of disability and reduced quality of life [].Elderly patients are at higher risk of mortality, …
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It was noted that compounds 44 (K i = 1.6 ± 0.2 µM), 45 (K i = 0.90 ± 0.10 µM) and 46 (K i = 0.61 ± 0.06 µM) displayed the greatest affinity towards Bcl-2. The binding affinity of compound 46 towards Bcl-2 is comparable to that of WL-276, while compounds 44 and 45 exhibited approximately 3.2 times and 1.8 times less potent binding than WL ...
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Dizüstü bilgisayarlarda kullanıcıların el hareketini komutlara dönüştüren sistem geliştirildi: Typealike. Bilim insanları, bir dizüstü bilgisayar kullanıcısının el hareketleriyle bilgisayara komut vermesi sağlayacak Typealike adlı bir sistem geliştirdi. Sistem 36 farklı hareketi algılayabiliyor. 10 Ocak 2022, 21:30 (1 ay)
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lar, éste se mostrará completo (todos los cables, conectores y espigas) dentro del grupo. Por ejemplo, el Relé de parada automática es probable que pueda hallarse en el grupo 30, o sea que en ese lugar éste se mostrará completo. No obstante, es posible que el mismo componente se muestre parcialmente en otro
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